Nuclear fission is the splitting of a heavy nucleus into two smaller nuclei, usually after absorbing a neutron. The process releases energy and typically emits additional neutrons.
Nuclear fusion is the joining of two light nuclei to form a heavier nucleus. If the products are more tightly bound, energy is released.
In OCR A questions, never just say “energy is released because things split” or “because nuclei join”. The mark-scoring explanation is that the products have a higher binding energy per nucleon, so total binding energy increases and the difference is released.
Heavy nuclei
Uranium-235 and plutonium-239 are common fissile fuels because they can undergo induced fission after absorbing a slow neutron.
Light nuclei
Hydrogen isotopes such as deuterium and tritium are used in fusion because the Coulomb barrier is lower than for heavier nuclei.
Energy source
In both cases, a small mass defect corresponds to a large energy release because c² is enormous.